Benztropine compounds and uses thereof
AssigneeThe United States of America, as represented by the Secretary, Department of Health and Human Services
InventorsAmy Hauck Newman, Mu-Fa Zou, Jonathan L. Katz
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Abstract
Disclosed are benztropine analogs having the formula (I) in which Ar is a C6-C20 monocyclic aryl group or a C10-C20 bicyclic aryl group or a heteroaryl, heterocyclic, or arylheterocyclic group having 2 to 12 carbon atoms and one or more heteroatoms selected from the group consisting of N, O, S, P, and any combination thereof; m=1 to 5; n=1 to 3; and R1 to R4 are as described in the specification; or a pharmaceutically acceptable salt or solvate thereof; pharmaceutical compositions and use thereof, e.g., in treating mental disorders.
Claims6
A compound or salt thereof, wherein the compound is selected from the group consisting of
A compound or salt thereof, wherein the compound is selected from the group consisting of:
A compound or salt thereof, wherein the compound is
- wherein R1 is selected from the group consisting of C4-C12 alkyl, 2-aminoethyl, [2-(1H-indol-3-yl)-ethyl]-, and C1-C12 aminoalkyl.
Dependencies are inferred from the claim text.