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US 8,383,340 B2Granted
Method for purifying RNA on a preparative scale by means of HPLC
AssigneeCureVac AG
InventorsThomas Ketterer, Florian Von Der Mulbe, Ladislaus Reidel, Thorsten Mutzke
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Abstract
The application describes a method for the preparative purification of RNA, which method is distinguished in that the RNA is purified by means of HPLC using a porous reversed phase as the stationary phase. The use of the porous reversed phase in this HPLC method is also described.
Claims26
A method for purifying RNA on a preparative scale, wherein the RNA is purified by HPLC or low or normal pressure liquid chromatography using a porous reversed phase as stationary phase and a mobile phase, wherein the porous reversed phase is a porous non-alkylated polystyrenedivinylbenzene.
Dependencies are inferred from the claim text.