Fluid processing device including size-changing barrier
AssigneeApplied Biosystems, LLC
InventorsUmberto Ulmanella, Debjyoti Banerjee, Konrad Faulstich, Aldrich Lau, Jun Xie
Life of this patent
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Abstract
A diagnostic device is provided that includes a plurality of retainment regions interconnected through at least one fluid processing passageway or separated by at least one barrier. A fluid flow modulator can be provided in the fluid processing passageway if a fluid processing passageway is provided. The barrier and/or fluid flow modulator can comprise a polysaccharide, a derivative of a polysaccharide, or a combination thereof. For example, the barrier can comprise a chitosan material.
Claims12
A fluid processing device comprising:
- a microfluidic chip comprising a flow passageway;
- a plurality of retainment regions, at least two of the retainment regions each being in fluid communication with the flow passageway;
- and
- at least one fluid flow modulator configured to be completely filled in the flow passageway, wherein the at least one fluid modulator is configured to prevent any fluid flow and to dissolve when contacted with water, to increase the size of a fluid communication between the at least two retainment regions, wherein the fluid flow modulator is configured to dissolve in a predetermined length of time based on a size of the fluid flow modulator, and wherein the at least one fluid flow modulator comprises a polysaccharide.
A fluid processing device comprising:
- a microfluidic chip comprising a flow passageway;
- and
- at least one valve arranged in the flow passageway, the at least one valve comprising a fluid flow modulator configured to be completely filled in the flow passageway so as to prevent any fluid flow, and wherein the fluid flow modulator is configured to dissolve when contacted with water to increase a fluid communication through the flow passageway, wherein the fluid flow modulator is configured to dissolve in a predetermined length of time based on a size of the fluid flow modulator, and wherein the fluid flow modulator comprises a polysaccharide.
A fluid processing device comprising:
- a microfluidic chip having a substrate;
- a plurality of retainment regions formed in or on the substrate, comprising at least a first retainment region and a second retainment region;
- a flow passageway;
- and
- wherein the first retainment region and the second retainment region are in fluid communication with the flow passageway;
- and
- a fluid flow modulator configured to be completely filled in the flow passageway so as to prevent any fluid flow, and wherein the fluid flow modulator is separating the first retainment region from the second retainment region, wherein said fluid flow modulator comprises a polysaccharide and is configured to dissolve when contacted with water to increase a fluid communication between the first retainment region and the second retainment region, wherein the fluid flow modulator is configured to dissolve in a predetermined amount of time based on a size of the fluid flow modulator.
Dependencies are inferred from the claim text.