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US 8,378,041 B2Granted
Method of preparing a star polymer macromonomer
AssigneeThe Trustees of Columbia University in the City of New York
InventorsJeremiah Johnson, Jeffrey T. Koberstein, Nicholas J. Turro
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Abstract
The present invention relates to methods for preparing degradable model networks from any monomer functionality with any degradation methodology. It is based on the use of Atom-Transfer Radical Polymerization CLICK chemistry and a tetrafunctional initiator having terminal halogen groups to form the desired product.
Claims5
A method of preparing a star polymer macromonomer, comprising:
- a) preparing a tetrafunctional initiator having terminal halogen groups, wherein the initiator contains a degradable linker for each of the terminal halogen groups, the degradable linker selected from the group consisting of a photodegradable linker, an ozonolyzable linker, and a biodegradable linker;
- b) using the tetrafunctional initiator, polymerizing a first monomer through ATRP to form a polymeric halide having the terminal halogen groups;
- c) modifying the polymeric halide through a post-polymerization transformation to replace the terminal halogen groups with desired functional end groups, wherein the desired functional end groups are selected from the group consisting of hydroxyl, acrylate, and azide.
Dependencies are inferred from the claim text.