Drug solution filling plastic ampoule and process for producing the same

A production method for a drug solution filling plastic ampoule comprising the steps of:

• molding a container body having a mouth by holding a tubular parison between lower split mold pieces and forming a void in the parison, the parison having three or more layers including an innermost layer composed of a polyolefin, an intermediate layer composed of blends of 20 to 50 wt % of polyolefin and 50 to 80 wt % of polycycloolefin to provide the container body with a steam permeation preventing capability and a drug permeation preventing capability and an outermost layer composed of a polyolefin,
• a thickness of the intermediate layer being from 11.8 to 35.3% of a total thickness of the three or more layers;
• filling a drug solution in the container body;
• and
• holding the mouth of the container body between upper split mold pieces to form a fusion-bonded portion which seals the mouth of the container body and a holder tab which is connected to the fusion-bonded portion to be used for wrenching off the fusion-bonded portion to open the mouth of the container body.