Polymer coatings on medical devices
AssigneeBiotectix, LLC
InventorsChristopher John Pickett, Timothy James Boote, Saad Khalil Ibrahim, Jane Marie Knott, John Douglas Tolland
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Abstract
A medical device, for example a stent, has a surface which in use contacts body tissue, wherein said surface has on it a biocompatible coating layer comprising a polymer having covalently bound allyl-terminated pendent groups, said pendent groups comprising a moiety selected from -0-CH2—CH═CH2—S—CH2—CH═CH2—S(=0)-CH2—CH═CH2—Se—CH2—CH═CH2 and —Se (=0 J-CH2—CH═CH2. This surface has good biocompatibility and can bind strongly to a metallic surface. The polymer may be made from an electropolymerisable monomer, e.g. a pyrrole.
Claims14
A medical device having a surface which in use contacts body tissue, wherein said surface has on it a biocompatible coating layer comprising a polymer having allyl-terminated pendent groups covalently attached to the polymeric chain, said pendent groups comprising a moiety selected from the group consisting of:
- —O—CH2—CH═CH2;
- —S—CH2—CH═CH2;
- and —S(═O)—CH2—CH═CH2;
- and
- wherein the polymer is an electropolymerized polymer.
A method of manufacture of a medical device comprising the step of forming a biocompatible polymeric layer by electropolymerisation of one or more types of monomer, wherein at least one of the types of monomer includes a covalently bound allyl-terminated pendent group, said pendent group comprising a moiety selected from the group consisting of:
- —O—CH2—CH═CH2;
- —S—CH2═CH2;and —S(═O)—CH2—CH═CH2.
Dependencies are inferred from the claim text.