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US 8,338,127 B2Granted
Testing a mammal for presence, progression or stage of a shock condition
AssigneeAnazyme
InventorJohn Rodenrys
Life of this patent
Estimating the term…
Abstract
Methods and kits for diagnosis and staging of non-septic shock are presented in which one or more protease activities are measured from a biological sample to so identify and/or stage non-septic shock. Most preferably, at least two protease activities are correlated, however, additional or alternative markers may also be measured.
Claims6
A method of testing a mammal for presence, progression or stage of a shock condition, comprising:
- obtaining a blood sample from the mammal and removing a cellular fraction from the blood to so obtain a serum or plasma fraction;
- measuring activity of trypsin in the serum or plasma fraction to obtain a test result;
- and
- correlating the test result with at least one of presence, progression and stage of non-septic hypovolemic shock in the mammal, wherein the step of correlating uses a corresponding test result of a healthy mammal, and wherein an increased trypsin activity as compared to the healthy mammal is indicative of the at least one of the presence, progression and stage of non-septic hypovolemic shock.
1 more element
Dependencies are inferred from the claim text.