Back to results
US 8,333,996 B2Granted
Calcium phosphate delivery vehicle and adjuvant
AssigneeEtex Corporation
InventorsD. Duke Lee, Maria Aiolova
Life of this patent
Estimating the term…
Abstract
An improved calcium phosphate delivery vehicle or adjuvant with incorporated adjuvanticity enhancing means and methods of producing same are disclosed. The adjuvant can be fabricated to desired formulations as appropriate and based on the intended purpose. Particle sizes can be adjusted to enhance adjuvant activity. Other supplemental materials may be added as desired and in appropriate proportions to selectively elicit preferred components of the immune system and to enhance the adjuvant's effect on the host response.
Claims9
A delivery composition comprising:
- a) a calcium phosphate comprising an amorphous calcium phosphate (ACP) or a poorly crystalline apatitic (PCA) calcium phosphate;
- and
- b) an antigen or vaccine;
- wherein said composition is formulated as an injectable paste that hardens in an endothermic reaction at body temperature to form a poorly crystalline apatitic calcium phosphate.
1 more element
Dependencies are inferred from the claim text.