Natural rubber latex having reduced allergenicity and method of making
AssigneeVystar Corporation
InventorsWilliam R. Doyle, Matthew P. Clark, Travis W. Honeycutt
Life of this patent
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Abstract
A rubber latex composition is disclosed having reduced allergenicity. Methods for producing a rubber latex composition having reduced allergenicity are also disclosed.
Claims16
A treated liquid natural rubber latex composition comprising:
- field latex that has been treated, prior to vulcanization, with an aluminum hydroxide slurry and 0.1 parts per hundred rubber of surfactant, wherein the aluminum hydroxide slurry is a combination of 1 parts per hundred rubber of 10% ammonium hydroxide and 0.5 parts per hundred rubber aluminum hydroxide;
- less than 3 μg of antigenic protein per gram of composition;
- and
- depleted amounts of proteins, lipids, and lutoids as compared to the field latex prior to being treated,
- wherein the depleted amounts of proteins, lipids and lutoids in the treated liquid natural rubber latex composition results in improved optical properties of the treated liquid natural rubber latex as compared to the field latex prior to being treated, and
- wherein the improved optical properties are measured by noticing at least one of a cleaner appearance, reduced color, or increased translucency as compared to field latex prior to being treated.
A treated natural rubber latex article comprising less than 3 μg/dm2 of antigenic protein and formed from a natural rubber latex composition treated, prior to vulcanization, with an aluminum hydroxide slurry and 0.1 parts per hundred rubber of surfactant, wherein the aluminum hydroxide slurry is a combination of 1 parts per hundred rubber of 10% ammonium hydroxide and 0.5 parts per hundred rubber aluminum hydroxide, the treated natural rubber latex article having improved optical properties as compared with an untreated natural rubber latex article, wherein the improved optical properties results from the removal of antigenic proteins complexed with aluminum hydroxide, and the removal of proteins, lipids and lutoids that were present in the natural rubber latex composition prior to being treated and wherein the improved optical properties are measured by noticing at least one of a cleaner appearance, reduced color, or increased translucency as compared to field latex prior to being treated.
A pre-vulcanized treated liquid natural rubber latex composition comprising:
- less than 3.0 μg/g of antigenic protein as measured by an ELISA inhibition assay;
- and
- depleted amounts of proteins, lipids, and lutoids as measured by noticing at least one of a cleaner appearance, reduced color, or increased translucency as compared to untreated field latex,
- wherein the treated liquid natural rubber latex has improved optical properties as compared to the untreated field latex.
Dependencies are inferred from the claim text.