Methods for improving kidney function
AssigneeFibroGen, Inc.
InventorsStephen J. Klaus, Qingjian Wang, Thomas B. Neff
Life of this patent
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Abstract
The invention relates to methods for improving renal (kidney) function. Methods for decreasing blood urea nitrogen (BUN), for increasing glomerular filtration rate (GFR), and for decreasing serum creatinine are also provided.
Claims10
A method for improving kidney function in a subject having impaired kidney function, the method comprising administering to the subject an effective amount of an agent that inhibits hypoxia inducible factor (HIP) hydroxylase activity.
A method for increasing glomerular filtration rate (GFR) in a subject having a decreased GFR, the method comprising administering to the subject an effective amount of an agent that inhibits RIF hydroxylase activity.
Dependencies are inferred from the claim text.