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US 8,299,271 B2Granted
Solid tartrate salts of DPP-IV inhibitors
AssigneePhenomix Corporation
InventorsZhen-Ping Wu, David Alan Campbell, Julie M. Cherrington
Life of this patent
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Abstract
This invention relates to DPP-IV inhibitory citrate or tartrate salts of pyrrolidinylaminoacetyl pyrrolidine boronic acid compounds that are physically and chemically stable, substantially non-deliquescent solids under ambient conditions.
Claims3
A solid form of a tartrate salt hydrate of a pyrrolidine compound of formula
- or a cyclic form thereof of formula
- or a mixture thereof, wherein the solid form comprises about 8-14% water by weight and is substantially non-hygroscopic when exposed to atmosphere at a relative humidity of up to 40 to 60% at about 25° C.
Dependencies are inferred from the claim text.