Methods for preparing diazonamides

A compound of formula (I):

• or a salt thereof;
• wherein:
• R1 is C1-C4 alkyl;
• R2 is H or Me;
• R3 is —NR4R5;
• R4 is H, or C1-C4 alkyl;
• R5 is H, or C1-C8 alkyl, C1-C8 heteroalkyl, C6-C14 arylalkyl, C6-C14 heteroarylalkyl, arylsulfonyl, trialkylsilyl, or alkoxycarbonyl, each of which may be optionally substituted;
• or —C(═X)R′ where X is O, S, or NH, and R′ is optionally fluorinated C1-C8 alkyl, C2-C8 alkenyl, C5-C12 aryl, or C6-C14 arylalkyl, each of which may be optionally substituted;
• R6 is H, or an arylalkyl, arylsulfonyl, acyl or alkoxycarbonyl;
• R7 is H, or halo, —CN, optionally substituted C1-C6 acyl, —COOR8, or —C(O)NR92;
• R8 is H, or C1-C8 alkyl, C2-C8 alkenyl, C5-C6 aryl, C6-C14 arylalkyl, or trialkylsilyl;
• R9 is H, or C1-C8 alkyl, C2-C8 alkenyl, C5-C6 aryl, C6-C14 arylalkyl, C6-C14 heteroarylalkyl, —OH, or C1-C4 alkoxy, each of which may be optionally substituted;
• or two R9 on the same N can optionally cyclize to form a ring;
• and
• Y′ is H or halo, and Y is halo or —OR10, where R10 is H, or is optionally fluorinated alkylsulfonyl or arylsulfonyl.