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US 8,299,219 B2Granted
Polypeptides, polynucleotides encoding same, antibodies thereagainst and methods of using same for diagnosing and treating cancer and skeletal disorders
AssigneeRamot at Tel-Aviv University Ltd.
InventorsDafna Benayahu, Irena Shur
Life of this patent
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Abstract
An isolated polypeptide is provided, comprising an amino acid sequence being at least 88% homologous to SEQ ID NO: 15 (human) as determined by BlastP using default parameters, the isolated polypeptide being capable of promoting cell adhesion and/or cell homing.
Claims4
An antibody being capable of specifically binding a polypeptide comprising an amino acid sequence as set forth in SEQ ID NO:
- 15, and being capable of binding a peptide consisting of an amino acid sequence selected from the group consisting of SEQ ID NO:
- 13, SEQ ID NO:
- 23, SEQ ID NO:
- 25, SEQ ID NO:
- 26 and SEQ ID NO:
- 27, the antibody being capable of neutralizing cell adhesion activity and/or cell homing activity of said polypeptide.
3 more elements
Dependencies are inferred from the claim text.