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US 8,299,106 B2Granted
Compositions of kinase inhibitors and their use for treatment of cancer and other diseases related to kinases
AssigneeBoston Biomedical, Inc.
InventorsChiang Jia Li, Ji-Feng Liu, Youzhi Li, Wei Li, Harry Rogoff
Life of this patent
Estimating the term…
Abstract
The present invention relates to novel thiazole-substituted indolin-2-ones as inhibitors of CSCPK and related kinases; to methods of inhibiting cancer stem cells by using a kinase inhibitor; to pharmaceutical compositions containing such compounds; and to methods of using such compounds in the treatment of a protein kinase related disorder in a mammal; and to processes of making such compounds and intermediates thereof.
Claims6
A compound selected from the group consisting of:
- and an enantiomer, diastereomer, tautomer, or pharmaceutically acceptable salt or solvate thereof.
Dependencies are inferred from the claim text.