Aminoisoquinoline thrombin inhibitor with improved bioavailability
AssigneeMSD Oss B.V.
InventorsRobert Gilfillan, David Jonathan Bennett
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Abstract
The invention relates to the compound N-(2-oxo-2-propoxyethyl)-β-phenyl-D-phenyl-alanyl-N-[(1-amino-6-iso-quinolinyl)methyl]-L-prolinamide or a pharmaceutically acceptable salt thereof, to a pharmaceutical composition comprising said compound, as well as to the use of the compound for the manufacture of a medicament for treating or for preventing thrombin mediated diseases.
Claims5
The compound N-(2-oxo-2-propoxyethyl)-β-phenyl-D-phenylalanyl-N-[(1-amino-6-isoquinolinyl)methyl]-L-prolinamide or a pharmaceutically acceptable salt thereof.
The compound N-(carboxymethyl)-β-phenyl-D-phenylalanyl-N-[(1-amino-6-isoquinolinyl)methyl]-L-prolinamide or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.