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US 8,299,061 B2Granted
Inhibitors of diacylglycerol acyltransferase
AssigneeEli Lilly and Company
InventorsMacklin Brian Arnold, Thomas James Beauchamp, Emily Jane Canada, Erik James Hembre, Jianliang Lu, John Robert Rizzo, John Mehnert Schaus, Qing Shi
Life of this patent
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Abstract
This invention provides compounds of formula I: or a pharmaceutically acceptable salt thereof; as well as a method for treating obesity, a method for treating diabetes, and a pharmaceutical composition.
Claims16
A compound of the formula
- or a pharmaceutically acceptable salt thereof;
- wherein
- R1 is selected from the group consisting of H, F, Cl, —CF3, —CH3, —OH, —O(C1-C4 alkyl), —O-cyclopropyl, —O—CH2-phenyl, —OC(H)F2, and —OCF3;
- R2 is selected from the group consisting of H and —CH3;
- R3 is selected from the group consisting of H and —CH3;
- provided that at least one of the group consisting of R2 and R3 is H;
- and
- n is 1, 2, or 3.
5 more elements
A compound of the formula
- or a pharmaceutically acceptable salt thereof.
A compound of the formula:
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.