Pharmaceutical compositions and methods for improved bacterial eradication
AssigneeShionogi & Co., Ltd.
InventorsHenry H. Flanner, Robert Guttendorf, Donald Treacy, Susan P. Clausen, Beth A. Burnside
Life of this patent
Estimating the term…
Abstract
A process for treating a bacterial infection with an antibiotic, comprising: administering to a patient with a bacterial infection a product that includes a modified release dosage form containing an antibiotic, said product being administered once-a-day in a dosage and for a number of days that provides a Total T>MIC sufficient to achieve at least the minimum amount of bacterial eradication for treatment of said bacterial infection.
Claims10
A process for treating a patient for at least one of pharyngitis or tonsillitis, caused by, or suspected to be caused by, an infection of said patient by Streptococcus pyogenes, said process for treating comprising:
- orally administering to said patient 775 mg of amoxicillin once a day, for ten days;
- wherein said amoxicillin is administered in a pharmaceutical product comprising an immediate release dosage form, a first delayed release dosage form and a second delayed release dosage form, wherein said first delayed release dosage form initiates release of amoxicillin after said immediate release dosage form initiates release of amoxicillin, and wherein said second delayed release dosage form initiates release of amoxicillin after said first delayed release dosage form initiates release of amoxicillin, whereby a Total T>MIC sufficient to achieve at least an 85% bacterial eradication rate is achieved in the patient.
Dependencies are inferred from the claim text.