Methods and compositions for the treatment of cancer
AssigneeQuintessence Biosciences, Inc.
InventorsJohn A. Kink, Laura E. Strong, Mark N. Shahan
Life of this patent
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Abstract
The present invention is directed toward the delivery of toxic agents to pathogenic cells, particularly cancer cells. In some embodiments, the toxic agent is a human ribonuclease or similar agent that is toxic to cells.
Claims9
A method for inhibiting tumor growth in a human subject having a cancer selected from the group consisting of breast, lung, prostate, pancreatic, skin, colon, ovarian, head-neck, liver, bladder, cervical, testicular, stomach, thyroid, esophageal, or renal cancer, the method comprising parenterally administering a pharmaceutical composition comprising recombinantly produced and purified wild type human ribonuclease 1 (wthRNase 1) to said subject in an amount effective for inhibiting the tumor growth of the cancer.
A method for inhibiting tumor growth in a human subject having a cancer selected from the group consisting of breast, lung, prostate, and pancreatic cancer, the method comprising the step of parenterally administering 15 to 300 mg/kg body weight of a pharmaceutical composition comprising an effective amount of recombinantly produced and purified wild type human ribonuclease 1 (wthRNase 1) to said subject.
Dependencies are inferred from the claim text.