Back to results
US 8,298,586 B2Granted
Variable density tissue graft composition
AssigneeACell, Inc.
InventorsRodney W. Bosley, Jr., Clay Fette
Life of this patent
Estimating the term…
Abstract
Disclosed are tissue graft compositions made of materials having different densities, methods of making, and methods of treatment for restoring tissues in a patient.
Claims23
A method for manufacturing a tissue graft composition, comprising:
- providing a first layer of planar biological material having a first density;
- providing a second layer of planar biological material comprising a second density that is less than the density of the first layer of material;
- introducing perforations into the first layer of planar biological material;
- introducing columns into the second layer of planar biological material;
- and
- compressing the first layer and the second layer of material together wherein the columns of the second layer of material are introduced into the perforations of the first layer of material to join the first layer to the second layer of material.
3 more elements
A method for manufacturing a tissue graft composition, comprising:
- providing a first layer of planar biological material having a first density;
- providing a second layer of planar biological material comprising a second density that is less than the density of the first layer of material;
- introducing raised members into the first layer of planar biological material;
- introducing depressed members complementary to the raised members into the second layer of planar biological material;
- and
- compressing the first layer and the second layer of material together wherein the raised members of the first layer of material intercalates with the depressed members of the second layer of material thereby joining the first layer to the second layer.
3 more elements
A tissue graft composition, comprising:
- at least two layers,
- wherein a first of said at least two layers comprises an extracellular matrix material, and has a plurality of raised elements, and a first density;
- and
- wherein a second of said at least two layers has a plurality of depressions, and a second density that is different from said first density;
- wherein each of said first and said second layers have a first planar surface and a second planar surface;
- and
- wherein each of said at least two layers partially overlaps an adjacent layer.
4 more elements
A method for restoring tissue damage of a joint, skin, an abdominal body wall, a thoracic body wall, a tendon, a ligament, or a hernia, comprising:
- providing a composition comprising at least two layers, wherein a first of said at least two layers comprises an extracellular matrix material, has a plurality of raised elements and a first density, wherein said second of said at least two layers has a plurality of depressions a second density which differs from said first density, wherein each of said first and second layers have a first planar surface and a second planar surface, and wherein each of said two layers at least partially overlapping the other layer overlaps an adjacent layer;
- and
- applying said composition to said joint, skin, abdominal body wall, thoracic body wall, tendon, ligament, or hernia.
Dependencies are inferred from the claim text.