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US 8,298,567 B2Granted
Hyperbranched polyurea delivery system for binding and release of growth factors
AssigneeMichigan Molecular Institute
InventorJin Hu
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Abstract
The present invention provides a polymer delivery system for the in vivo binding and release of growth factors, preferably orthobiologic GF, comprising a hyperbranched polymer having physiologically-acceptable anionic phosphorous groups. The hyperbranched polymer is preferred to be a polyurea with phosphonate anions. This polymer can be cross-linked to form a network and provide a coating for implanted devices.
Claims10
A polymer delivery system comprising a polyurea hyperbranched polymer (HBP) having physiologically-acceptable anionic phosphorous groups for the in vivo binding and release of growth factors.
Dependencies are inferred from the claim text.