Systems for producing multilayered particles, fibers and sprays and methods for administering the same
AssigneeTerapia Celular, LN, Inc.
InventorsGustavo Larsen, Ruben Spretz, Raffet Velarde-Ortiz, David Vu, Luis Nunez
Life of this patent
Estimating the term…
Abstract
Capsules and particles with at least one encapsulated and/or entrapped agent, such as therapeutic agent, imaging agents, and other constituents may be produced by electrohydrodynamic processes. More particularly, the agent encapsulated in a vehicle, capsule, particle, vector, or carrier may maximize treatment and/or imaging of malignant cancers while minimizing the adverse effects of treatment and/or imaging.
Claims18
An electrohydrodynamic system for producing a capsule having at least one encapsulated agent, said system comprising:
- a hollow tube having an external wall and an interior configured to receive a core fluid;
- a shell liquid source surrounding only a fraction of a length of the external wall of said hollow tube such that at least a discharge end of the hollow tube is not surrounded by the shell liquid source;
- a core fluid supply tube arranged to supply the core fluid to said interior of said hollow tube;
- a shell liquid supply tube arranged to supply a shell liquid to said shell liquid source;
- a collector electrode positioned above the shell liquid source configured to collect the produced capsule;
- an extractor body positioned between the shell liquid source and the collector electrode;
- and
- an electric potential source to subject the core fluid and the shell liquid to an electric potential to cause the core fluid and shell liquid to form a jet including an at least two-fluid electrically charged fluid by incorporation of the extractor body.
A system for producing a capsule having at least one encapsulated agent, said system comprising:
- a plurality of hollow tubes, each hollow tube having an external wall, the plurality of hollow tubes being located adjacent each other and forming a shape;
- an encasement surrounding only a fraction of a length of the external walls of said plurality of hollow tubes such that at least discharge ends of the hollow tubes are not surrounded by the encasement, the encasement having a shape that corresponds to the shape of the plurality;
- a core fluid supply tube arranged to supply a core fluid to an interior of said plurality of hollow tubes;
- a shell fluid supply tube arranged to supply a shell fluid;
- a collector electrode configured to collect the produced capsule;
- an extractor body located between an open end of the hollow tubes and the collector electrode;
- and
- an electric potential source to subject the core fluid and the shell fluid to an electric potential to cause the core and shell fluids to form a jet having an at least two-fluid electrically charged fluid by incorporation of the extractor body.
Dependencies are inferred from the claim text.