# US 8,295,435 B2 · Cardiac target tracking

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- Number: US 8,295,435 B2
- Document ID: US8295435B2
- Status: Granted
- Kind: B2
- Application number: 12/354,710
- Filed: 2009-01-15
- Published: 2009-07-16
- Granted: 2012-10-23
- Earliest claimed: 2008-01-16
- Assignees: Accuray Incorporated
- Inventors: James Wang; Dongshan Fu; Calvin R. Maurer, Jr.
- Web page: https://patentgrep.com/patent/US8295435B2

## CPC

- A61N 5/1049: {for verifying the position of the patient with respect to the radiation beam}
- A61N 5/10: X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy (A61N5/01 takes precedence)
- A61N 5/1082: {having multiple beam rotation axes}
- G06T 7/33: using feature-based methods
- A61B 6/4458: {the source unit or the detector unit being attached to robotic arms}
- A61N 5/1037: {taking into account the movement of the target, e.g. 4D-image based planning}
- A61N 5/1067: {in real time, i.e. during treatment}
- A61N 5/1068: {Gating the beam as a function of a physiological signal}
- A61N 5/107: {in real time, i.e. during treatment}
- A61N 2005/1061: {using an x-ray imaging system having a separate imaging source}
- G06T 2207/10081: Computed x-ray tomography [CT]
- G06T 2207/10121: Fluoroscopy
- G06T 2207/10124: Digitally reconstructed radiograph [DRR]
- G06T 2207/30048: Heart; Cardiac
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)
- G06T: IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

Systems and methods for tracking cardiac targets are disclosed. The cardiac targets may be tracked dynamically. The process may include registering a cardiac target at different phases of a cardiac cycle. Movement of the cardiac target can be determined by correlating respiratory motion and cardiac pumping motion. Radiation treatment can then be delivered to the cardiac target taking into account the movement of the cardiac target.

## Claims

### Claim 1

A method of tracking cardiac targets comprising:
receiving a cardiac pumping signal;
receiving a respiratory signal;
receiving a radiation treatment plan developed using four dimensional image data;
developing a cardiac motion model of a cardiac target using the cardiac pumping signal, the respiratory signal and the four dimensional image data;
identifying a blurring effect of cardiac motion on a dose distribution in the radiation treatment plan,
generating a modified radiation treatment plan that takes into account the identified blurring effect; and
delivering radiation in accordance with the modified radiation treatment plan.

### Claim 2 (depends on 1)

The method of claim 1, wherein delivering radiation comprises tracking the radiation delivery based on a correction generated from the cardiac pumping signal.

### Claim 3 (depends on 1)

The method of claim 1, wherein delivering radiation comprises moving the radiation beam based on the respiratory signal of the cardiac target.

### Claim 4 (depends on 1)

The method of claim 1, wherein delivering radiation comprises tracking the radiation delivery based on a correction generated from the cardiac pumping signal and moving the radiation beam based on the respiratory signal of the cardiac target.