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US 8,286,665 B2Granted
Multiplexed latching valves for microfluidic devices and processors
AssigneeThe Regents of the University of California
InventorsRichard A. Mathies, William H. Grover, Erik C. Jensen
Life of this patent
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Abstract
Membrane valves and latching valve structures for microfluidic devices are provided. A demultiplexer can be used to address the latching valve structures. The membrane valves and latching valve structures may be used to form pneumatic logic circuits, including processors.
Claims8
A microfluidic logic circuit comprising:
- an array of membrane valves, the array comprising a latching valve and a plurality of logic valves, wherein the logic valves are part of a single monolithic structure and wherein the latching valve and the logic valves are in fluid communication with each other to form a logic gate structure, and wherein the latching valve comprises:
- a valve input configured to receive application of a pressure or a vacuum;
- a valve control configured to receive application of a pressure, vacuum, or neither;
- a valve output;
- and a first normally-closed elastomer membrane configured such that the application of a pressure or a vacuum to the valve input and application of a pressure, a vacuum or neither to the valve control causes the membrane to deflect according to the following pneumatic logic:
- Valve Input
- Valve Control
- Valve Output
- Pressure
- Pressure
- Closed
- Pressure
- Vacuum
- Open
- Pressure
- Neither
- Open if input pressure large
- enough to force valve open
- Vacuum
- Pressure
- Closed
- Vacuum
- Vacuum
- Open
- Vacuum
- Neither
- Closed;
- and further wherein each of the logic valves comprises a valve input configured to receive application of a pressure or a vacuum;
- a valve control configured to receive application of a pressure, vacuum, or neither;
- a valve output;
- and a normally-closed elastomer membrane configured such that the application of a pressure or a vacuum to the valve input and application of a pressure, a vacuum or neither to the valve control causes the membrane to deflect according to said pneumatic logic.
28 more elements
Dependencies are inferred from the claim text.