Methods of determining relative genetic likelihoods of an individual matching a population

A computer-implemented method of determining an individual's relative likelihood of a genetic match with one or more local European populations as compared to a generic index population comprising

• determining, using a computer, a genetic likelihood of the individual belonging to at least one local European population selected from a group of reference local European populations, wherein said individual's likelihood of belonging to the at least one local European population is determined from a product of the frequencies of occurrence in the local European population of genetic markers present in the individual;
• determining, using a computer, a genetic likelihood of the individual belonging to a European generic index population, comprising the group of reference local European populations, wherein said individual's likelihood of belonging to a European generic index population is determined from a product of the frequencies of occurrence in the European generic index population of genetic markers present in the individual;
• and
• comparing, using a computer, the likelihood of the individual belonging to the at least one local European population to the likelihood of the individual belonging to the European generic index population to determine the individual's relative likelihood of a genetic match with the one or more local European populations;
• wherein the European generic index population is an average or median of all European populations.

A computer-implemented method of determining an individual's relative likelihood of a genetic match with one or more local populations as compared to a generic index population comprising:

• determining, using a computer, a genetic likelihood of the individual belonging to at least one local population selected from a group of reference local populations, by comparing, using a computer, genetic markers present in the individual at a plurality of genetic loci, to a product of frequencies of occurrence of said genetic markers in the at least one local population;
• determining, using a computer, a genetic likelihood of the individual belonging to a generic index population comprising the group of reference local populations, by comparing, using a computer, genetic markers present in the individual at a plurality of genetic loci, to a product of frequencies of occurrence of said genetic markers in the generic index population;
• and
• comparing, using a computer, the likelihood of the individual belonging to the at least one local population to the likelihood of the individual belonging to the generic index population to determine the individual's relative likelihood of a genetic match with the one or more local populations.

A computer-implemented method comprising

• (a) determining, using a computer, an individual's relative likelihood of a genetic match with a local population as compared to a generic index population;
• comprising:
• determining, using a computer, a genetic likelihood of the individual belonging to at least one local population selected from a group of reference local populations, by comparing genetic markers present in the individual at a plurality of genetic loci, to a product of frequencies of occurrence of said genetic markers in the at least one local population;
• determining, using a computer, a genetic likelihood of the individual belonging to a generic index population, said generic index population comprising the group of reference populations by comparing, using a computer, genetic markers present in the individual at a plurality of genetic loci, to a product of frequencies of occurrence of said genetic markers occurring in the generic index population;
• and
• comparing, using a computer, the likelihood of the individual belonging to the at least one local population to the likelihood of the individual belonging to the generic index population;
• (b) determining, using a computer, one or more additional individual's relative likelihood of having a genetic match with the local population as compared to the generic index population, by generating a distribution of likelihood scores for population j using the population's allele frequencies;
• wherein said one or more additional individuals are selected from actual individuals or simulated individuals;
• and
• (c) comparing, using a computer, the individual's relative likelihood to the one or more additional individual's relative likelihood.