US 8,283,457 B2 · Nucleic acid molecule capable of binding to rabbit-derived IgG antibody

Abstract

The present invention provides a nucleic acid molecule having an ability to bind to a rabbit anti-mouse IgG antibody, which can be prepared more easily than an antibody and has a binding ability equal to or higher than that of an antibody. The nucleic acid molecule according to the present invention may have the sequences set forth in SEQ ID NOS: 1 to 5. The nucleic acid molecule according to the present invention may be a nucleic acid having an ability to bind to a rabbit IgG antibody, which substantially has homology to its sequence. The nucleic acid molecule according to the present invention may have a binding constant (KD) of 1.18×10−7 (M) or less to the rabbit IgG antibody.

Claims6

Dependent claims

An isolated or purified RNA molecule comprising the polynucleotide sequence of any one of SEQ ID NOs:

1-5 wherein the binding constant (KD) of said RNA molecule to the rabbit IgG antibody is 1.18×10−7 (M) or less.

Dependencies are inferred from the claim text.

Facts

Application

12/516,293Filed 22 Nov 2007

Priority

JP 2006-31711324 Nov 2006

Published

US 2010/0222559 A12 Sep 2010

Granted

9 Oct 2012

Term ends

Not estimatedThe source records don’t support an estimate.

Classification5 codes

C12Q 1/6883
Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes: for diseases caused by alterations of genetic material
C12N 15/115
DNA or RNA fragments; Modified forms thereof ; Non-coding nucleic acids having a biological activity: aptamers, i.e. nucleic acids binding a…
C12N 2310/16
Type of nucleic acid: aptamers
C12Q
Measuring or testing processes involving enzymes, nucleic acids or microorganisms

Nucleic acid molecule capable of binding to rabbit-derived IgG antibody

Life of this patent

Nucleic acid molecule capable of binding to rabbit-derived IgG antibody

Life of this patent

Abstract

Claims6