Kit for prediction of pre-eclampsia
AssigneePerkinElmer LAS, Inc.
InventorsLucilla Poston, Paul Townsend Seed, Beverley Jane Hunt, Lucy Charlotte Chappell
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Abstract
The present invention relates to a method of predicting pre-eclampsia (PE). The present invention also relates to a diagnostic kit for performing a method of predicting PE. In particular, the method determining the level of two or more markers selected from placenta growth factor (PlGF), plasminogen activator inhibitor-1 (PAI-1), plasminogen activator inhibitor-2 (PAI-2) and leptin.
Claims17
A kit for specific prediction of pre-eclampsia (PE) by determining levels of two or more markers in a maternal sample, wherein the kit comprises immunoassay reagents capable of measuring the levels of the markers, wherein the markers are selected from the group consisting of:
- placenta growth factor (PlGF), plasminogen activator inhibitor-1 (PAI-1), plasminogen activator inhibitor-2 (PAI-2), leptin, the ratio of leptin/PlGF concentrations, and the ratio of PAI-1/PAI-2 concentrations.
Dependencies are inferred from the claim text.