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US 8,283,447 B2Granted
Immunosuppressive polypeptides and nucleic acids
AssigneePerseid Therapeutics LLC
InventorsErik E. Karrer, Madan M. Paidhungat, Steven H. Bass, Margaret Neighbors, Juha Punnonen, Steven J. Chapin
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Abstract
The invention provides immunosuppressive polypeptides and nucleic acids encoding such polypeptides. In one aspect, the invention provides mutant CTLA-4 polypeptides and nucleic acids encoding mutant CTLA-4 polypeptides. Compositions and methods for utilizing such polypeptides and nucleic acids are also provided.
Claims8
An isolated or recombinant CTLA-4 polypeptide comprising a polypeptide sequence having at least 96% identity to the polypeptide sequence of SEQ ID NO:36.
Dependencies are inferred from the claim text.