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US 8,283,440 B2Granted
Snapin and methods for regulation of microtubule assembly and dendrite growth and branching
OwnerBonnie L. Firestein-Millerinventor
Life of this patent
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Abstract
Fragments of snapin important for interaction with cypin and thus regulating microtubule assembly are provided. Also provided are methods of use of said fragments and kits to facilitate said methods.
Claims5
A kit comprising:
- at least a portion of cypin comprising a collapsin response mediator protein (CRMP) homology domain comprising the amino acid sequence of SEQ ID NO:
- 4, at least the portion of cypin being capable of binding at least a portion of tubulin;
- and
- at least a portion of snapin comprising a carboxyl-terminal coiled-coil domain comprising the amino acid sequence of SEQ ID NO:
- 2, at least the portion of snapin being capable of binding at least the portion of cypin.
2 more elements
Dependencies are inferred from the claim text.