Thieno-pyridine derivatives as MEK inhibitors

A compound of Formula (I), or a pharmaceutically acceptable salt or N-oxide thereof:

• wherein
• R1 is hydrogen, halogen or C1-6 alkyl;
• R2 is halogen or C1-6 alkyl;
• R3 is hydrogen, cyano, —CO2Ra, —CONRbRc or —CON(ORb)Rc;
• Ra is C1-6 alkyl;
• Rb is hydrogen, optionally substituted C1-6 alkyl, optionally substituted C3-7 cycloalkyl, optionally substituted C3-7 cycloalkyl(C1-6)alkyl, optionally substituted aryl, optionally substituted aryl(C1-6)alkyl, optionally substituted C3-7 heterocycloalkyl, optionally substituted C3-7 heterocycloalkyl(C1-6)alkyl, optionally substituted heteroaryl or optionally substituted heteroaryl(C1-6)alkyl;
• Rc is hydrogen or C1-6 alkyl optionally substituted with one or more hydroxyl groups;
• or
• Rb and Rc are taken together with the nitrogen atom to which they are attached to form a cyclic group selected from optionally substituted azetidinyl, optionally substituted pyrrolidinyl, optionally substituted piperidinyl, optionally substituted morpholinyl, optionally substituted thiomorpholinyl, optionally substituted piperazinyl, optionally substituted homopiperidinyl, optionally substituted homomorpholinyl and optionally substituted homopiperazinyl.