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US 8,283,313 B2Granted
Methods of increasing platelet and hematopoietic stem cell production
AssigneeJanssen Pharmaceutica NV
InventorsBrian R. MacDonald, Kenneth Kaushansky
Life of this patent
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Abstract
A method of increasing hematopoietic stem cell production is disclosed. The method includes administering a TPO mimetic compound to a subject. Pharmaceutical compositions including a TPO mimetic compound and a pharmaceutically acceptable carrier are also disclosed.
Claims9
A method of increasing hematopoietic stem cell production in a subject comprising a step of administering a thrombopoietin (TPO) mimetic compound to said subject, wherein the TPO compound has the following sequence:
- wherein (2-Nal) is β-(2-naphthyl)alanine and Sar is sarcosine.
Dependencies are inferred from the claim text.