Back to results
US 8,283,165 B2Granted
Matrices and media for storage and stabilization of biomolecules
AssigneeGenVault Corporation
InventorsMichael Hogan, Michael Saghbini, Chunnian Shi, David Wong
Life of this patent
Estimating the term…
Abstract
The present invention provides compositions useful for biomolecule storage comprising a water soluble inorganic compound, a stabilizer, or a combination thereof. The present invention also provides methods of using the compositions of the invention to store biomolecules in the dry state and in solution, as well as sample carriers and kits comprising compositions of the invention.
Claims43
A dry-state matrix comprising:
- boric acid or a corresponding salt of boric acid;
- a plasticizer, wherein the plasticizer is a poly-alcohol;
- a hydroxyl radical scavenger;
- and
- an RNase inhibitor,
- wherein the matrix is in a solid or dry form which can be converted to a liquid form by suspending, re-hydrating, or solubilizing the matrix in water.
3 more elements
An aqueous medium comprising:
- boric acid or a corresponding salt of boric acid;
- a plasticizer, wherein the plasticizer is a poly-alcohol;
- a hydroxyl radical scavenger;
- and
- an RNase inhibitor,
- wherein said aqueous medium is in a liquid state.
3 more elements
Dependencies are inferred from the claim text.