System and method for increasing polymer/nanopore interactions

A method, for increasing nanopore and molecule interactions comprising:

• providing a nanopore at an interactive region within a first analyte chamber, with the nanopore including first and second opposing sides;
• introducing a sample solution to the first analyte chamber through an access port, the sample solution containing a molecule of interest;
• and
• applying a voltage to first and second driving electrodes, both arranged on the first side of the nanopore within the first analyte chamber, to produce an electric field to drive the molecule of interest from the access port to the interactive region to increase the number of target molecules within the interactive region for interaction with the nanopore.

A method for increasing nanopore and molecule interactions comprising:

• providing a nanopore at an interactive region within a first analyte chamber, with the nanopore including first and second opposing sides;
• introducing a sample solution to the first analyte chamber through an access port, the sample solution containing a molecule of interest;
• and
• applying a voltage to first and second driving electrodes, both arranged on the first side of the nanopore within the first analyte chamber to produce an electric field to drive the molecule of interest from the access port to the interactive region to increase the probability of an event wherein the molecule of interest interacts with the nanopore, and
• applying a voltage to third and fourth electrodes located on the first and second opposing sides of the nanopores respectively to produce an electric field across the nanopore.