US 8,283,114 B2Granted

Genes of an otitis media isolate of nontypeable Haemophilus influenzae

AssigneesNationwide Children's Hospital, Inc., The Board of Regents of the University of Oklahoma

InventorsLauren O. Bakaletz, Robert S. Munson, Jr., David W. Dyer

Life of this patent

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Abstract

The invention relates to the polynucleotide sequence of a nontypeable stain of Haemophilus influenzae (NTHi) and polypeptides encoded by the polynucleotides and uses thereof. The invention also relates to NTHi genes which are upregulated during or in response to NTHi infection of the middle ear and/or the nasopharynx.

Claims7

Dependent claims

An isolated polynucleotide comprising the nucleotide sequence of SEQ ID NO:

970.

Dependencies are inferred from the claim text.

Facts

Application: 11/917,368Filed 15 Jun 2006 · continuation in part
Priority: 6 Mar 2003
Published: US 2011/0135646 A19 Jun 2011
Granted: 9 Oct 2012
Term ends: Not estimatedThe source records don’t support an estimate.

Classification25 codes

C07K 14/285
From bacteria: from Pasteurellaceae , e.g. Haemophilus influenza
A61K 9/0046
Galenical forms characterised by the site of application: ear
A61K 39/102
Bacterial antigens: pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
A61P 27/14
Ophthalmic agents: decongestants or antiallergics

Family

Application60/453,134Us provisional application · filed 6 Mar 2003
Application10/795,159Parent of this continuation-in-part · filed 5 Mar 2004
Application60/691,214Us provisional application · filed 16 Jun 2005
US 2011/0135646 A1Pre-grant publication · published 9 Jun 2011
US 7,241,867 B2Parent of this continuation-in-part
US 2005/0221439 A1Published application
US 8,283,114 B2This patent

From the US filing history. Foreign family members aren’t listed.

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