A process for packaging dianhydrohexitol, comprising the introduction of said dianhydrohexitol into a packaging made from a material based on a thermoplastic polymer, and the sealing of said packaging, said process being characterized by the fact that the packaging material comprises at least one layer of thermoplastic polymer containing at least 0.1% by weight of at least one antioxidant (layer (A)), said layer (A) either being directly in contact with the dianhydrohexitol or being separated from the latter by a layer made from a thermoplastic polymer (layer (B)) having a thickness at most equal to 150 μm, and by the fact that the thermoplastic polymer of the layer (A) and/or of the layer (B) is chosen independently from polyethylene, polypropylene, copolymers of ethylene and of propylene, and mixtures thereof.