Loading patent…
AssigneeN.V. Nutricia
InventorsEsther Jacqueline de Kort, Robert Johan Joseph Hageman, Martine Groenendijk, Patrick Joseph Gerardus Hendrikus Kamphuis
Estimating the term…
The invention pertains to a liquid composition for preventing and/or treating memory decline and/or cognitive dysfunction, Alzheimer's, Parkinson's and/or dementia, said composition comprising: (i) at least 50 mg nucleoside and/or nucleotide per 100 ml; (ii) between 0.2 and 10 grams protein per 100 ml; (iii) between 0.05 and 3 wt. % of 5 thickener, based on total weight of the composition. The thickener is preferably selected from the group consisting of cellulose, xanthan gum, gellan gum, alginate, guar gum, locust bean gum, gum karaya, gum tragacanth, carrageenan, and mixtures thereof. The composition preferably has a loss factor tan δ between 0.1 and 100, as measured at any strain in the range of 1 100% at 0.1 Hz and 20° C. It is particularly found that a thickener selected from the group consisting of gellan gum, xanthan gum and cellulose greatly reduces sedimentation.
A method for treating memory decline and/or cognitive dysfunction, Alzheimer's disease, Parkinson's disease and/or dementia, the method comprising administering to a person in need thereof a composition comprising:
A liquid composition comprising:
Dependencies are inferred from the claim text.
Drawings are temporarily unavailable. Open the PDF at USPTO
From the US filing history. Foreign family members aren’t listed.
Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin: cellulose;…
Of vegetable origin: cellulose; Derivatives thereof, e.g. ethers
Containing gelling or thickening agents: of microbial origin, e.g. xanthan or dextran
Of microbial origin, e.g. xanthan or dextran: gellan
About 1 year 11 months of term left · ends 26 Sep 2028 (estimated)
The invention pertains to a liquid nucleotides/nucleosides-containing nutritional product, preferably a product containing uridine-containing nucleotides/nucleosides, and its preparation, and to its use in improving neurodegenerative disorders, preferably for combating memory decline and/or cognitive dysfunction, Alzheimer's, Parkinson's and/or dementia, and for promoting or supporting healthy brain function.
Memory loss, dementia and reduced brain function are major problems, particularly in elderly. Significant effort is put in the treatment and/or prevention of these disorders related with impaired nerve functioning. Persons older than 50 years of age are particularly prone to developing such disorders.
WO-A-2006/031683 teaches to administer a composition comprising a uridine in order to improve cognitive and neurological functions in a subject. Uridine, in particular in the form of uridine monophosphate (UMP), is a nutrient that increases synthesis and release of neurotransmitters and membrane synthesis by neural cells and brain cells. Nutritional products containing uridine and high concentrations of macro- and micronutrients are administered to elderly patients, with the aim to prevent memory decline.
In one aspect the present invention provides a liquid composition for preventing and/or treating neurodegenerative disorders, preferably selected from the group consisting of memory decline, cognitive dysfunction, Alzheimer's, Parkinson's and/or dementia, said composition comprising: at least 50 mg nucleoside and/or nucleotide per 100 ml; and between 0.2 and 10 grams protein per 100 ml.
In a further aspect the present method provides a method for the treatment and/or prevention of memory decline and/or cognitive dysfunction, Alzheimer's, Parkinson's and/or dementia, said method comprising the administration of a composition comprising: at least 50 mg nucleoside and/or nucleotide per 100 ml; and between 0.2 and 10 grams protein per 100 ml.
In yet a further aspect the present invention provides a liquid comprising at least 50 mg nucleoside and/or nucleotide per 100 ml; and between 0.2 and 10 grams protein per 100 ml.