Water-soluble ginger root extract
AssigneeKao Corporation
InventorsYusuke Shibuya, Shigeru Moriwaki, Naoko Tsuji
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AssigneeKao Corporation
InventorsYusuke Shibuya, Shigeru Moriwaki, Naoko Tsuji
Estimating the term…
Provided are a water-soluble ginger root extract which is a water extract or a hydrous alcohol extract of a ginger root and is substantially free of gingerols; and a hair growth inhibitor and a preparation for external use each containing the extract. The water-soluble ginger root extract of the present invention causes less skin irritation because of being substantially free of gingerols, and has excellent body-hair growth inhibiting effects, so that it is useful as a hair grown inhibitor and a preparation for external use, each having a high degree of safety.
A method of inhibiting hair growth comprising contacting the area for which hair growth inhibition is desired in a subject in need thereof with an external preparation comprising a water-soluble ginger root extract which comprises a water extract or a hydrous alcohol extract of a ginger root and which is substantially free of gingerols, wherein said hydrous alcohol extract of a ginger root has a maximum alcohol content of 70% v/v.
Dependencies are inferred from the claim text.
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Zingiberaceae: zingiber, e.g. garden ginger
Angiosperms [Magnoliophyta]: liliopsida [monocotyledons]
Drugs for dermatological disorders
Drugs for dermatological disorders: for baldness or alopecia
About 9 months of term left · ends 13 Jul 2027 (estimated)
1. Field of the Invention
The present invention relates to a water-soluble ginger root extract substantially free of gingerols.
2. Description of the related art
FIG. 1 illustrates the results of componential analysis by HPLC (A: water-soluble ginger root extract (Example 1), B: ginger root extract (Comparative Example).
The term “ginger root” as used herein means a root of Zingiber officinale Roscoe belonging to the Zingiberaceae plant family.
The term “substantially free of gingerols” means that the extract does not substantially contain gingerols such as 1-gingerol, 6-gingerol, 8-gingerol and 10-gingerol and in particular, the amount of 6-gingerol is not greater than 0.5 ppm, preferably not greater than a detection limit in HPLC analysis under the below-described conditions.
<HPLC Analysis Conditions>