Identification and molecular characterisation of proteins, expressed in the Ixodes ricinus salivary glands
OwnerEdmond Godfroid, Yves Decrem +3inventors
InventorsEdmond Godfroid, Yves Decrem, Luc Vanhamme, Alex Bollen, Gérard Leboulle
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Abstract
The invention relates to a new polynucleotide which encodes a polypeptide expressed in the salivary glands of ticks, more particularly the Ixodes ricinus arthropod tick, during the slow-feeding phase of the blood meal have. The polynucleotide and related polypeptide may be used in different constructions and for different applications which are also included in the present invention.
Claims9
An isolated polypeptide consisting of the polypeptide sequence of SEQ ID NO:
- 36.
An isolated polypeptide consisting of the polypeptide sequence of SEQ ID NO:
- 36, wherein at least one amino acid in SEQ ID NO:
- 36 has asubstitution group, preferably selected from the group consisting of amide, acetyl, phosphoryl, and/or glycosyl groups.
An isolated fusion protein comprising a polypeptide consisting of the polypeptide sequence of SEQ ID NO:
- 36 fused to a heterologous polypeptide.
An isolated polypeptide comprising a polypeptide consisting of the polypeptide sequence of SEQ ID NO:
- 36 and at least one additional heterologous amino acid sequence which contains secretory or leader sequences, pro-sequences, sequences which help in purification or additional sequences for stability during recombination protection.
Dependencies are inferred from the claim text.