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US 8,275,552 B1Granted
Toxicity reporting system
AssigneeUniversity of South Florida
InventorAndrea Trotti, III
Life of this patent
Estimating the term…
Abstract
The present invention is a method for communicating and forecasting the extent of toxicity of a given treatment program by deploying a uniform multi-modality grading system, and capturing significant high-grade events within defined risk periods to create a treatment-specific summary rating or classification of the toxicity experience.
Claims10
A method for determining a toxicity rating of a treatment program, the method comprising:
- identifying a toxicity grading system appropriate for the treatment program, wherein the toxicity grading system ranks the severity of adverse events related to a treatment program;
- recording significant adverse events occurring during an administration of the treatment program within a first predetermined period of time and recording significant adverse events occurring during the administration of the treatment program within a second predetermined period of time, wherein a significant adverse event is an adverse event ranked by the toxicity grading system as being severe or life-threatening and wherein the second predetermined period of time is after the first predetermined period of time;
- determining an acute toxicity domain of the treatment program by calculating a median number of significant adverse events occurring during the first predetermined period of time;
- determining an adverse late effects domain by calculating a median number of significant adverse events occurring during the second predetermined period of time;
- determining the toxicity rating of the treatment program from a sum of the acute toxicity domain and the adverse late effects domain;
- and
- comparing the toxicity rating of the treatment program with a toxicity rating of other treatment programs to determine a favorable treatment option for a patient;
- wherein each of the above method steps are performed according to an automated process using software tools.
5 more elements
Dependencies are inferred from the claim text.