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US 8,273,860 B2Granted
Imatinib immunoassay
AssigneeSaladax Biomedical Inc.
InventorsSalvatore J. Salamone, Jodi Blake Courtney, Alexander Volkov
Life of this patent
Estimating the term…
Abstract
Novel conjugates and immunogens derived from imatinib and monoclonal antibodies generated by these immunogens are useful in immunoassays for the quantification and monitoring of imatinib or its pharmacologically active salts in biological fluids.
Claims15
A compound of the formula:
- or its pharmacologically active salts;
- wherein Y is an organic spacing group;
- X is a terminal functional group capable of binding to a carrier containing an amino or thiol group through said amino or thiol group and;
- p is an integer from 0 to 1.
1 more element
A composition comprising a carrier containing a polymer having either a reactive thiol or amino group conjugated with a compound of the formula:
- or its pharmacologically active salts;
- wherein Y is an organic spacing group;
- X is a terminal functional group involved in the binding to said carrier through said amino or thiol group and;
- p is an integer from 0 to 1.
1 more element
An immunogen comprising an immunogenic carrier containing a polymer having either a reactive thiol or amino group conjugated with a compound of the formula:
- or its pharmacologically active salts;
- wherein Y is an organic spacing group;
- X is a terminal functional group involved in the binding to said carrier through said amino or thiol group and;
- p is an integer from 0 to 1.
1 more element
Dependencies are inferred from the claim text.