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US 8,273,791 B2Granted
Compositions, kits and regimens for the treatment of skin, especially décolletage
AssigneeJr Chem, LLC
InventorsJosé E. Ramirez, Joseph R. Faryniarz
Life of this patent
Estimating the term…
Abstract
Compositions, kits and regimens for treatment of damaged skin, especially décolletage, include application of a retinoid, hydroquinone or hydroquinone derivatives, and a composition containing a multi-metal complex.
Claims18
A method of treating skin comprising:
- administering to an area of skin a first treatment and, after a predetermined period of time, a second treatment,
- the first treatment comprising topically applying a retinoid, a hydroquinone, and a multi-metal complex;
- the second treatment comprising topically applying a hydroquinone and a multi-metal complex
- wherein the multi-metal complex employed in the first treatment and in the second treatment comprises a central malonate unit, wherein the central malonate unit bridges one or more copper molecules and one or more zinc molecules by coordinate bonding.
1 more element
A method comprising:
- pre-mixing a retinoid with a hydroquinone-containing composition to form a pre-mixed formulation;
- applying the pre-mixed formulation to the skin;
- and
- applying a composition comprising a multi-metal complex to the skin
- wherein the multi-metal complex comprises a central malonate unit, wherein the central malonate unit bridges one or more copper molecules and one or more zinc molecules by coordinate bonding.
2 more elements
A method of treating skin comprising:
- topically applying a retinoid and a hydroquinone to an area of non-facial skin;
- and
- topically applying a composition comprising at least one multi-metal complex to the area of non-facial skin previously treated with retinoid and hydroquinone, wherein the multi-metal complex comprises a central malonate unit, wherein the central malonate unit bridges one or more copper molecules and one or more zinc molecules by coordinate bonding.
A method of treating skin comprising:
- topically applying a retinoid and a hydroquinone to an area of non-facial skin;
- and
- topically applying a composition comprising at least one multi-metal complex to the area of non-facial skin previously treated with retinoid and hydroquinone, wherein the multi-metal complex comprises a central unit, wherein the central unit is derived from at least one compound selected from polycarboxylic acids and amino acids having at least two carboxylic acid groups and the center unit bridges one or more copper molecules and one or more zinc molecules by coordinate bonding.
A method of treating skin comprising:
- topically applying a retinoid and a hydroquinone to an area of non-facial skin;
- and
- topically applying a composition comprising at least one multi-metal complex to the area of non-facial skin previously treated with retinoid and hydroquinone, wherein the multi-metal complex comprises a reaction product of a compound having two or more carboxylic acid groups with basic salts of two or more coordination elements selected from one or more of copper, silver, gold, aluminum, scandium, titanium, vanadium, chromium, manganese, iron, cobalt, nickel, copper, zinc, gallium, yttrium, zirconium, niobium, molybdenum, technetium, ruthenium, rhodium, palladium, silver, cadmium, and indium, wherein the two or more coordination elements are joined to a central unit derived from the compound having two or more carboxylic acid groups.
Dependencies are inferred from the claim text.