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US 8,273,789 B2Granted
Biologically active taxane analogs and methods of treatment by oral administration
AssigneeTapestry Pharmaceuticals, Inc.
InventorsJames D. McChesney, Gilles Tapolsky, David L. Emerson, John Marshall, Tauseef Ahmed, Allen Cohn, Michael Kurman, Manuel Modiano
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Abstract
The present invention relates to a novel chemical compound of formula S-(1): for use in the treatment of cancer, to compositions containing said compound, methods of manufacture and combinations with other therapeutic agents.
Claims32
A compound of the formula:
- wherein the stereochemistry of the 7,9-vinyl acetal in said compound has S-configuration in a diastereomeric excess of at least 90%.
A compound of the formula:
Dependencies are inferred from the claim text.