Process for preparation of 1-alkyl-5-benzoyl-1H-tetrazole derivatives

A process for preparation of 1-alkyl-5-benzoyl-1H-tetrazole derivative comprising:

• a step 1 of reacting a ketoamide derivative represented by formula (I):
• (in formula (I), A represents a halogen atom, alkyl group, haloalkyl group, alkoxy group, haloalkoxy group, alkyl sulfonyl group, optionally substituted aryl group, cyano group or nitro group;
• n represents an integer of 0 to 5 (when n is 2 or more, plural A may be the same or different from each other);
• Y represents an alkyl group) with a halogenating agent to obtain an imidoyl halide derivative represented by formula (II):
• (in formula (II), A, n and Y are as defined above;
• X represents a halogen atom);
• and
• a step 2 of reacting the imidoyl halide derivative represented by formula (II) with an azide represented by formula (III):
• M(N3)M (III)
• (in formula (III), M represents an alkali metal or alkali earth metal;
• m represents 1 or 2) to obtain a 1-alkyl-5-benzoyl-1H-tetrazole derivative represented by formula (IV):
• (in formula (IV), A, n and Y are as defined above).