Use of modified pyrimidine compounds to promote stem cell migration and proliferation
AssigneeUniversity of Central Florida Research Foundation, Inc.
InventorsKiminobu Sugaya, Tingyu Qu
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Abstract
This invention provides cells and methods for stimulating proliferation and migration of endogenous and exogenous mammalian stem cells in vivo and in vitro. The invention provides reagents and methods for efficiently proliferating mammalian stem cells in an animal in need thereof and producing stem cells that can be re-introduced into an animal in need thereof to alleviate neurological and corporal disorders.
Claims4
A method of increasing cognitive function in a human by stimulating proliferation, migration or both proliferation and migration of endogenous human neural stem cells in the cerebral cortex of said human, the method comprising administering an effective amount of MS-818, for an effective period to the human.
Dependencies are inferred from the claim text.