Methods of treating obesity using PYY[3-36]
AssigneeAmylin Pharmaceuticals, Inc.
InventorsRichard A. Pittner, Andrew A. Young, James R. Paterniti, Jr.
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Abstract
Methods and compositions are disclosed to treat metabolic disorders such as obesity, diabetes, and increased cardiovascular risk comprising administering a therapeutically effective amount of a PYY or a PYY agonist.
Claims7
A method of reducing food intake comprising peripherally administering to a human subject, via a parenteral route, an amount of PYY agonist analog effective to reduce food intake, wherein the PYY agonist analog is PYY[3-36], and wherein the amount is in the range of about 100 μg/kg to 1,000 μg/kg per day in a single or divided dose.
A method of reducing body weight or reducing body weight gain comprising peripherally administering to a subject having obesity an amount of PYY[3-36], wherein the amount is in the range of about 300 μg/kg to 1,000 μg/kg per day in a single or divided dose.
A method of reducing food intake and body weight comprising peripherally administering to a subject having obesity an amount of PYY[3-36], wherein the amount is in the range of about 300 μg/kg to 1,000 μg/kg per day in a single or divided dose.
A method of treating obesity comprising peripherally administering to a subject an amount of PYY[3-36], wherein the amount is in the range of about 300 μg/kg to 1,000 μg/kg per day in a single or divided dose.
Dependencies are inferred from the claim text.