Protein hydrolysate enriched in peptides inhibiting DPP-IV and their use
AssigneeCampina Nederland Holding B.V.
InventorJan-Willem Pieter Boots
Life of this patent
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Abstract
Disclosed is a protein hydrolysate having DPP-IV inhibiting activity, the hydrolysate being enriched in peptides having a length of 2-8 amino acids comprising at least one proline residue, an isolated peptide derivable from such a protein hydrolysate, or a mixture thereof, and the use of such protein hydrolysate or isolated peptide for the manufacture of a medicament, food supplement, beverage or food product for prophylaxis and/or treatment of a DPP-IV mediated condition, in particular chosen from the group of obesity, type 2 diabetes mellitus and an immunological disorder.
Claims10
A method for treatment a condition mediated by dipeptidyl peptidase IV (DPP-IV) selected from the group consisting of obesity, type 2 diabetes mellitus, and autoimmune disease, comprising administering to a subject in need thereof an effective amount of a composition comprising a protein hydrolysate enriched in peptides of 3-7 amino acids, wherein at least one said peptides is selected from the group consisting of MPLW (SEQ ID NO:
- 6), LPQYL (SEQ ID NO:
- 36), LPVPQ (SEQ ID NO:37), GPFP (SEQ ID NO:
- 32), PLLQ (SEQ ID NO:
- 33), VPYPQ (SEQ ID NO:
- 38), VPLGTQ (SEQ ID NO:
- 43), LPVPQK (SEQ ID NO:
- 44), KVLP (SEQ ID NO:
- 34), and LPL.
Dependencies are inferred from the claim text.