Wound healing compositions containing keratin biomaterials
AssigneeWake Forest University Health Sciences
InventorMark E. Van Dyke
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Abstract
Disclosed are keratin preparations for use in medical applications. Methods of treating wounds are provided, wherein keratin preparations are applied to the wound in a treatment effective amount. Methods of treating burn wounds are also provided. Surgical or paramedic aids are provided, comprising a substrate with keratin preparations provided thereon. Kits comprising keratin derivatives packaged in sterile form are also provided.
Claims58
A method of treating a wound in a subject in need thereof, said method comprising applying a composition comprising a keratin derivative, wherein said keratin derivative is at least 80% by weight of acidic alpha kerateine to said wound in an amount effective to treat said wound, wherein said wound is treated.
A method for treating a burn wound in a subject afflicted with a burn wound, said method comprising topically applying a composition comprising a keratin derivative, wherein said keratin derivative is at least 80% by weight of acidic alpha kerateine to said burn wound in an amount effective to treat said burn wound, wherein said burn wound is treated.
A method of treating a wound in a subject in need thereof, said method comprising applying a composition comprising a keratin derivative, wherein said keratin derivative is at least 80% by weight of acidic alpha keratose to said wound in an amount effective to treat said wound, wherein said wound is treated.
A method of treating a wound in a subject in need thereof, said method comprising applying a composition comprising a keratin derivative, wherein said keratin derivative is at least 80% by weight of basic alpha kerateine to said wound in an amount effective to treat said wound, wherein said wound is treated.
A method of treating a wound in a subject in need thereof, said method comprising applying a composition comprising a keratin derivative, wherein said keratin derivative is at least 80% by weight of basic alpha keratose to said wound in an amount effective to treat said wound, wherein said wound is treated.
A method for treating a burn wound in a subject afflicted with a burn wound, said method comprising topically applying a composition comprising a keratin derivative, wherein said keratin derivative is at least 80% by weight of basic alpha kerateine to said burn wound in an amount effective to treat said burn wound, wherein said burn wound is treated.
A method for treating a burn wound in a subject afflicted with a burn wound, said method comprising topically applying a composition comprising a keratin derivative, wherein said keratin derivative is at least 80% by weight of acidic alpha keratose to said burn wound in an amount effective to treat said burn wound, wherein said burn wound is treated.
A method for treating a burn wound in a subject afflicted with a burn wound, said method comprising topically applying a composition comprising a keratin derivative, wherein said keratin derivative is at least 80% by weight of basic alpha keratose to said burn wound in an amount effective to treat said burn wound, wherein said burn wound is treated.
A method of treating a wound in a subject in need thereof, comprising:
- applying a keratin derivative to said wound in an amount effective to treat said wound,
- wherein said keratin derivative is selected from the group consisting of:
- acidic alpha keratose, acidic alpha kerateine, basic alpha keratose, and basic alpha kerateine, and
- wherein said keratin derivative is produced by the process of fractionating a mixture comprising acidic and basic alpha keratin by ion exchange chromatography.
Dependencies are inferred from the claim text.