Autologous treatment of degenerated disc with cells
AssigneeDePuy Spine, Inc.
InventorsMohamed Attawia, Hassan Serhan, Thomas M. DiMauro, Melissa Grace, David Urbahns
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Abstract
The present invention relates to administering autologous uncultured cells into a diseased intervertebral disc.
Claims39
A method of treating degenerative disc disease in an intervertebral disc having a nucleus pulposus in a patient, comprising administering TGF-β and concentrated autologous uncultured mesenchymal stem cells from 7-10 ml of the patient's bone marrow into the degenerated intervertebral disc immediately following harvesting of the cells.
A method of treating degenerative disc disease in an intervertebral disc having a nucleus pulposus in a patient, comprising administering TGF-β and autologous uncultured mesenchymal stem cells from the patient's bone marrow into a degenerated intervertebral disc immediately following harvesting of the autologous uncultured mesenchymal stem cells in a formulation with a final volume of between about 0.5 mL and about 3.0 mL.
Dependencies are inferred from the claim text.