Protein-polymer conjugates

A peptide-polymer conjugate of the following formula:

• wherein
• each of R1, R2, R3, R4, and R5, independently, is H, C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, aryl, heteraryl, C3-8 cycloalkyl, or C3-8 heterocycloalkyl;
• each of A1 and A2, independently, is a polymer;
• each of G1, G2, and G3, independently, is a bond or a linking functional group;
• P is selected from the group consisting of an interferon-β, an erythropoietin, and a growth hormone, the nitrogen atom of the N-terminus of P being bonded to G3;
• m is 0 or an integer of 1-10;
• and
• n is an integer of 1-10.