Back to results
US 8,263,783 B2Granted
Process for the sulfinylation of a pyrazole derivative
AssigneeBASF SE
InventorsMartin Sukopp, Oliver Kuhn, Carsten Gröning, Michael Keil, Jon J. Longlet
Life of this patent
Estimating the term…
Loading patent…
Loading patent…
AssigneeBASF SE
InventorsMartin Sukopp, Oliver Kuhn, Carsten Gröning, Michael Keil, Jon J. Longlet
Estimating the term…
The present invention relates to a process for the sulfinylation of a pyrazole derivative, characterized in that 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-1H-pyrazole-3-carbonitrile (II) is reacted with a sulfinylating agent selected from trifluoromethylsulfinic acid, trifluoromethylsulfinic acid anhydride, and a trifluoromethylsulfinate alkaline or alkaline earth metal salt and mixtures of the acid and/or the salt(s), in the presence of at least one amine acid complex wherein the amine(s) are selected from tertiary amines and the acid(s) are selected from hydrofluoric, hydrochloric, hydrobromic and hydroiodic acid and sulfonic acid derivatives, and with the addition of a halogenating agent.
A process for preparing fipronil consisting essentially of sulfinylating 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-1H-pyrazole-3-carbonitrile (II) by reacting II with
Dependencies are inferred from the claim text.