Estrogen receptors and methods of use
AssigneeCreighton University
InventorZhao Yi Wang
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Abstract
The present invention provides isolated polypeptides having an amino acid sequence having at least 70% identity to SEQ ID NO:20, wherein the polypeptide has ER-α36 activity. The invention further provides methods for identifying agents that bind to such polypeptides, methods for detecting such polypeptides, and methods for altering the activity of such polypeptides. Also provided are antibodies that specifically bind to an amino acid sequence depicted at SEQ ID NO:1, or an immunogenic fragment thereof, and methods for making and using such antibodies.
Claims8
An isolated polypeptide comprising the amino acid sequence depicted at SEQ ID NO:
- 1 or an immunogenic fragment thereof, wherein the immunogenic fragment comprises at least 7 contiguous amino acids.
Dependencies are inferred from the claim text.